Dolittle makes use of well known filming location Blenheim Palace in Oxford which is used as Buckingham Palace as well as Cothay Manor being used as Dr Dolittle's manor and the small market town of Kirkby Lonsdale for the village scenes.
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After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures.